: a clotting factor produced primarily in the liver that circulates in an inactive form in blood plasma and in its activated form combines with factor X on the surface of platelets to accelerate the conversion of prothrombin to thrombin
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The factor V Leiden mutation puts people at higher risk for developing blood clots.
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Dr. Keith Roach, oregonlive, 8 Feb. 2022
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Dr. Keith Roach, oregonlive, 8 Feb. 2022
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“Factor V.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/factor%20V. Accessed 12 Mar. 2026.
Copy CitationMedical Definition
factor V
noun
: a globulin clotting factor produced primarily in the liver that circulates in an inactive form in blood plasma and in its activated form combines with factor X on the surface of platelets to accelerate the conversion of prothrombin to thrombin
called also accelerator globulin, labile factor, proaccelerin
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